{"id":2306,"date":"2025-06-09T11:02:28","date_gmt":"2025-06-09T18:02:28","guid":{"rendered":"https:\/\/blogschapman.wpenginepowered.com\/pharmacy\/2025\/06\/09\/patient-safety-award-recognizes-two-cusp-faculty\/"},"modified":"2025-06-09T11:02:28","modified_gmt":"2025-06-09T18:02:28","slug":"patient-safety-award-recognizes-two-cusp-faculty","status":"publish","type":"post","link":"https:\/\/blogs.chapman.edu\/pharmacy\/2025\/06\/09\/patient-safety-award-recognizes-two-cusp-faculty\/","title":{"rendered":"Patient Safety Award Recognizes Two CUSP Faculty"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2309 alignright\" src=\"https:\/\/blogs.chapman.edu\/pharmacy\/wp-content\/uploads\/sites\/65\/2025\/06\/Keykavous-Parang.jpg\" alt=\"\" width=\"179\" height=\"202\" \/>The second an<span style=\"font-weight: 400\"><a href=\"https:\/\/blogs.chapman.edu\/pharmacy\/wp-content\/uploads\/sites\/65\/2025\/06\/sun-yang.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-2308 alignleft\" src=\"https:\/\/blogs.chapman.edu\/pharmacy\/wp-content\/uploads\/sites\/65\/2025\/06\/sun-yang.jpg\" alt=\"\" width=\"152\" height=\"200\" \/><\/a>nual CUSP Patient Safety Award was presented to Keykavous Parang, Pharm.D., Ph.D, and Coco Yang, Ph.D., for their collaborative proposal \u201cPeptide-Drug Conjugates to Enhance Doxorubicin Safety: A Novel Strategy to Reduce Cardiotoxicity and Improve Patient Outcomes.\u201d Following recommendations of CUSP\u2019s Science and Patient Safety Committees, this award recognizes innovative research proposals by an individual or pair of faculty that show potential to significantly improve patient care.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Parang\u2019s and Yang\u2019s proposal has two ultimate aims. The first is to examine how peptide-drug conjugates (PDCs) reverse doxorubicin (DOX) resistance and mitigate cardiotoxicity (damage to the cardiovascular system, including the heart). The second is to explore the in vivo safety and therapeutic effectiveness of PEGylated and targeted PDCs. PEGylation refers to the process of adding polyethylene glycol to a molecule, which can increase the longevity and effectiveness of some drugs.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">By investigating these factors, Yang and Parang may be able to increase the effectiveness of DOX. DOX, alongside similar drugs, is currently limited by cardiotoxicity and long-term resistance. While it is a highly effective cancer treatment, DOX also has serious side effects that can weaken the patient. Increasing the half-life of DOX and decreasing the cardiotoxicity effect will improve its effectiveness and reduce side effects, and will contribute to a longer lifespan for patients undergoing chemotherapy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">CUSP practices and teaches patient-safety-first practices in both clinic and research settings. Through initiatives like the CUSP Patient Safety Award, we formally recognize the impact our faculty have in addressing critical issues in healthcare, developing effective interventions, and promoting a culture of safety and excellence.\u00a0<\/span><\/p>\n<p><em>This article was written by\u00a0<a href=\"https:\/\/www.linkedin.com\/in\/silas-fernandes-02bb3a215\/\" target=\"_blank\" rel=\"noopener noreferrer\">Silas Fernandes<\/a>.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The second annual CUSP Patient Safety Award was presented to Keykavous Parang, Pharm.D., Ph.D, and Coco Yang, Ph.D., for their [&hellip;]<\/p>\n","protected":false},"author":4726,"featured_media":2307,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"custom_author_name":"","chapman_pin_hero_slider":"","footnotes":""},"categories":[185,405,28,53],"tags":[3204,3205,3206,3207,3208,18,3209,3210,3211,403,1278,3212,3213,3214,3215,3216,3217,3071,3218,91,3219,3220,3221,3222,3223,3224,3225,3035,3226,3227,3228],"class_list":["post-2306","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-awards","category-faculty","category-patient-safety","category-research","tag-cancer-drug-development","tag-cancer-pharmacotherapy","tag-cancer-therapy-optimization","tag-cancer-treatment-innovation","tag-cardiotoxicity-reduction","tag-chapman-university-school-of-pharmacy","tag-chemotherapeutic-agent-improvement","tag-chemotherapy-side-effects","tag-clinical-safety-initiatives","tag-coco-yang","tag-cusp-patient-safety-award","tag-dox-resistance","tag-doxorubicin-safety","tag-drug-longevity","tag-drug-resistance-solutions","tag-healthcare-intervention-research","tag-improving-chemotherapy-outcomes","tag-improving-patient-outcomes","tag-in-vivo-drug-testing","tag-keykavous-parang","tag-oncology-drug-safety","tag-oncology-pharmacology","tag-patient-centered-research","tag-pdc-research","tag-pegylated-drug-delivery","tag-pegylation-benefits","tag-pegylation-in-pharmacology","tag-peptide-drug-conjugates","tag-safety-in-clinical-research","tag-targeted-cancer-therapies","tag-therapeutic-efficacy-research"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - 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