{"id":5756,"date":"2015-10-22T10:00:18","date_gmt":"2015-10-22T17:00:18","guid":{"rendered":"https:\/\/blogschapman.wpenginepowered.com\/scst\/2015\/10\/22\/science-blender-faking-a-cure-for-hiv\/"},"modified":"2015-10-22T10:00:18","modified_gmt":"2015-10-22T17:00:18","slug":"science-blender-faking-a-cure-for-hiv","status":"publish","type":"post","link":"https:\/\/blogs.chapman.edu\/scst\/2015\/10\/22\/science-blender-faking-a-cure-for-hiv\/","title":{"rendered":"Science Blender | Science Gone Wrong"},"content":{"rendered":"
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Throughout the year, we will be publishing essays from Professor Andrew Lyon<\/a>‘s\u00a0Honors 389\u00a0course\u00a0“The\u00a0Science Blender” . For the\u00a0first paper this term, students were asked to investigate the idea of \u00a0“science gone wrong”.\u00a0 Below is one student’s essay\u00a0on the topic.<\/em><\/p><\/blockquote>\n

Science in the modern era has unveiled answers to many obscure problems of\u00a0humankind. Frequently, news about a grand discovery appears in journals, and it is met by media attention, praise, validation and promising funding grants. However, the desire for fame and money has invoked in modern scientists the motivation to find loopholes to shorten their research. Starting with insignificant miscalculations, scientific fraud has evolved into serious legal issues. One of the recent examples of \u201cscience gone wrong\u201d is the scandal of Dong-Pyou Han, who earlier in 2015 faced a jail sentence for his misconduct.<\/p>\n

Dong-Pyou Han was a biomedical scientist and a former researcher at Iowa State University who engaged with\u00a0a research team for an HIV vaccine 2008-2013. According to the journal Nature<\/a><\/em>, in 2008, \u201cHan spiked rabbit blood samples with human HIV antibodies so that the vaccine appeared to have caused the animals to develop immunity to the\u00a0virus\u201d.<\/p>\n

With this faked discovery, he was able to receive millions of dollars from the National Institutes of Health (NIH). Although he proclaimed that this was just an accident, he failed to admit his falsified sample and instead continued his research. He later went on to join the research group recruited by Iowa University, which, as the Medical Daily<\/a><\/em> cited, meant, \u201cmore grant money came in and that led to other researchers attempting to replicate the results.”<\/p>\n

After several similar studies, in 2013, researchers from Harvard finally found the false sample in another test. The US Office of Research Integrity (ORI) cut the funding for Han, and he was forced to resign from Iowa State University. This was the end for Han’s career, yet it was the beginning of his legal troubles.<\/p>\n

Han\u2019s case has showed how the\u00a0phrase \u201cscience gone wrong\u201d extends into administrative systems. The case was further investigated by Senator Charles Grassley of Iowa, \u201cwho has a history of investigating misconduct in the biomedical sciences,\u201d according to\u00a0Nature<\/a><\/em>. The federal agencies finally charged Han\u00a0with felony in court earlier in 2015. Han was sentenced to 57 months in jail and fined $7.2 million for his misconduct.<\/p>\n

The case was not only a serious incident for the scientific research field but also for the legal system that supports it. The NIH and the ORI institutions, which were primarily in charge of the case, could not directly investigate and had to refer to another agency for inspections. The two also did not cooperate well on the case, and even stated<\/a> that, \u201cbenefit of criminal prosecution is unclear.\u201d\u00a0By practicing loose regulation, they had allowed Han to prolong his fraudulent research. In general, those institutions have opened the possibility of many more future\u00a0instances\u00a0of \u201cscience gone wrong\u201d.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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The case of Dong-Pyou Han has added another serious scandal to the science field. It not only reflects the term \u201cscience gone wrong,\u201d but also sets a notorious example of both scientists\u2019 misconduct and administrations\u2019 mismanagement.<\/p>\n<\/div>\n

About Honors 389: The Science Blender<\/strong><\/p>\n

Throughout Professor\u00a0Lyon’s Science Blender course,\u00a0students identify knowledge gaps that\u00a0prevent simple solutions to grand challenges, and then they develop strategies to address those\u00a0gaps. In this process, students also\u00a0become more conversant in the languages of different disciplines and how team-based problem solving benefits scientific pursuits.<\/p><\/blockquote>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Faking a Cure for HIV – Student Essay from the HON 389 Science Blender Course<\/p>\n","protected":false},"author":271,"featured_media":5757,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"custom_author_name":"Thang Nguyen","chapman_pin_hero_slider":"","footnotes":""},"categories":[20],"tags":[],"class_list":["post-5756","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-blender"],"yoast_head":"\nSchmid College of Science and Technology | Chapman Blogs<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.chapman.edu\/scst\/2015\/10\/22\/science-blender-faking-a-cure-for-hiv\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Science Blender | Science Gone Wrong - 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